A particular disorder might be described as “running in a family” if more than one person in the family has the condition. Some disorders that affect multiple family. Disorder definition, lack of order or regular arrangement; confusion: Your Disorder, brawl, disturbance, uproar are disruptions or interruptions of a peaceful situation. I hid behind the greenhouse doors, to see the meaning of this disorder. My stepbrother has been told he has bipolar disorder – what does this mean.